Overview
| Synonyms | HIST1H3A,H3FA,HIST1H3B,H3FL,HIST1H3C,H3FC,HIST1H3D,H3FB,HIST1H3E,H3FD,HIST1H3F,H3FI,HIST1H3G,H3FH,HIST1H3H,H3FK,HIST1H3I,H3FF,HIST1H3J,H3FJ,Histone H3.1,Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/ |
| Swissprot | P68431,Q71DI3,P84243 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat,Yeast |
| Immunogen | Recombinant Protein |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF,IP |
| Recommended dilution | WB 1:500-1:2000, IHC 1:50-300, IF 1:100-500, IP 1:100-1:300 |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Extracellular region or secreted,extracellular exosome,extracellular region,Nucleus,nuclear chromosome,nuclear chromosome, telomeric region,nuclear nucleosome,nucleoplasm,nucleus,Other locations:nucleosome,protein complex |
| Clone No. | Clone:5B1 |
| Isotype | IgG |
| Purification | Protein A purification |
| Conjugation | Unconjugated |
| Storageinstructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.4 |
| Background | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |